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KMID : 0614620230820010035
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Korean Journal of Gastroenterology
2023 Volume.82 No. 1 p.35 ~ p.39
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A Case of Transverse Myelitis Following Treatment with Atezolizumab for Advanced Hepatocellular Carcinoma
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Kim Kyung-Han
Baek Yang-Hyun
Kang Yeo-Wool
Yoon Byeol-A
Moon Sang-Yi
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Abstract
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The results of the IMbrave150 study have led to widespread use of the combination therapy of atezolizumab and bevacizumab as a first-line treatment for unresectable or metastatic hepatocellular carcinoma (HCC). Compared to traditional cytotoxic chemotherapy agents, immune checkpoint inhibitors show a spectrum of side effects ranging from mild side effects such as skin rash to potentially severe systemic effects such as myocarditis. We present a case of transverse myelitis diagnosed during the treatment of HCC with atezolizumab and bevacizumab combination therapy.
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KEYWORD
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Hepatocellular carcinoma, Atezolizumab, Transverse myelitis
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